Article
The glutathione biotransformation system and colorectal cancer risk in humans.
Scandinavian journal of gastroenterology. Supplement - 1 Jan 2001
Grubben M J, Nagengast F M, Katan M B, Peters W H
Abstract excerpt
Evidence for a protective role of the glutathione biotransformation system in carcinogenesis is growing. However, most data on this system in relation to colorectal cancer originate from animal studies. Here we review the human data. In humans, a significant association was found between glutathione S-transferase (GST) activity in the mucosa along the gastrointestinal tract and the corresponding tumour incidence....
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