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Article

Association of a sodium channel alpha subunit promoter variant with blood pressure.

Journal of the American Society of Nephrology : JASN - 1 Jan 2002

Iwai Naoharu, Baba Shunroku, Mannami Toshifumi, Ogihara Toshio, Ogata Jun

Abstract excerpt

The SCNNIA gene, which is located on human chromosome 12p13.3, encodes the alpha subunit of the amiloride-sensitive epithelial sodium channel, and mutations in SCNNIA can result in pseudohypoaldosteronism type I. It was postulated that genetic variations in SCNN1A could lead to an increased risk of hypertension. Sequence variations in SCNN1A were identified, and the association between these polymorphisms and BP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11752024
DOI: 10.1681/ASN.V13180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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