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Article

Alpha fetoprotein mediates HB x induced carcinogenesis in the hepatocyte cytoplasm

4 Apr 2015

Abstract excerpt

Although tumor-associated fetal protein AFP has demonstrated utility as a clinical tumor marker, the significance of intracellular AFP is still unclear. The aim of this study was to explore the role of cytoplasmic AFP during HBx induced carcinogenesis, which had not previously been recognized; 614 HCC patients were analyzed for correlation of HBV infection with AFP level, and much higher AFP levels were found in...

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PMID: 25846475
DOI: 10.1002/ijc.29548

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