Article
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.
Genes & development - 15 Dec 2001
Jackson E L, Willis N, Mercer K, Bronson R T, Crowley D, Montoya R, Jacks T, Tuveson D A
Abstract excerpt
Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin and the stages of progression of this tumor type are not well understood. We have developed a new model of lung adenocarcinoma in mice harboring a conditionally activatable allele of oncogenic K-ras. Here we...
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