Selection of candidate genes for population studies.

Abstract excerpt

A broad view of genetic susceptibility in humans suggests that high-penetrance hereditary genes cause a number of relatively uncommon tumours in the familial setting, while common cancers are Influenced by multiple susceptibility loci. Early investigations of the latter category focused on the role of genes In the metabolism of carcinogens (activation, detoxification) while current and planned studies extend to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carcinogens
• Share to Cytochrome P-450 Enzyme System
• Share to Genetic Predisposition to Disease