Article
Changes in predominance and diversity of genomic subtypes of Bordetella pertussis isolated in the United States, 1935 to 1999.
Emerging infectious diseases - 1 Jan 2002
Hardwick Terri Hawes, Cassiday Pamela, Weyant Robbin S, Bisgard Kristine M, Sanden Gary N
Abstract excerpt
Pulsed-field gel electrophoresis (PFGE) of Bordetella pertussis chromosomal DNA fragments generated by XbaI restriction has been used to subtype isolates for epidemiologic studies. To better understand the natural history of pertussis, we determined the PFGE profiles of 1,333 strains isolated in the United States from 1935 to 1999. Results showed a shift in prevalent profiles from the earliest to the latest study...
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