Article
Population diversity among Bordetella pertussis isolates, United States, 1935-2009.
Emerging infectious diseases - 1 Aug 2012
Schmidtke Amber J, Boney Kathryn O, Martin Stacey W, Skoff Tami H, Tondella M Lucia, Tatti Kathleen M
Abstract excerpt
Since the 1980s, pertussis notifications in the United States have been increasing. To determine the types of Bordetella pertussis responsible for these increases, we divided 661 B. pertussis isolates collected in the United States during 1935-2009 into 8 periods related to the introduction of novel vaccines or changes in vaccination schedule. B. pertussis diversity was highest from 1970-1990 (94%) but declined...
Topics
- Alleles
- Antigens, Bacterial
- Bordetella pertussis
- Disease Notification
- Fimbriae Proteins
- Genetic Variation
- Humans
- Minisatellite Repeats
- Multilocus Sequence Typing
- Pertussis Toxin
- Pertussis Vaccine
- United States
- Vaccination
- Virulence Factors, Bordetella