Article
Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas.
Oncogene - 16 Mar 2000
Di Renzo M F, Olivero M, Martone T, Maffe A, Maggiora P, Stefani A D, Valente G, Giordano S, Cortesina G, Comoglio P M
Abstract excerpt
A metastatic cancer develops by accumulation of mutations in genes that control growth, survival and spreading. The latter genes have not yet been identified. In lymph node metastases of head and neck squamous cell carcinomas (HNSCC), we found mutations in the MET oncogene, which encodes the tyro...
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