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Article

Helix-coil transition of PrP106-126: molecular dynamic study.

Proteins - 1 Dec 2001

Levy Y, Hanan E, Solomon B, Becker O M

Abstract excerpt

A set of 34 molecular dynamic (MD) simulations totaling 305 ns of simulation time of the prion protein-derived peptide PrP106-126 was performed with both explicit and implicit solvent models. The objective of these simulations is to investigate the relative stability of the alpha-helical conformation of the peptide and the mechanism for conversion from the helix to a random-coil structure. At neutral pH, the...

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PMID: 11746686
DOI: 10.1002/prot.1157

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GSS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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