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Article

Regional serotonin metabolism in the brain of transgenic mice lacking monoamine oxidase A.

Journal of neuroscience research - 1 Nov 2001

Popova N K, Gilinsky M A, Amstislavskaya T G, Morosova E A, Seif I, De Maeyer E

Abstract excerpt

The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the activity of tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin (5-HT) biosynthesis, and on the levels of 5-HT and 5-hydroxyindoleacetic acid (5-HIAA) in the midbrain, hypothalamus, hippocampus, striatum, amygdala, and frontal cortex was studied. It was shown that mice with a genetic MAO A knockout...

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Identifiers

PMID: 11746359
DOI: 10.1002/jnr.1234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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