Article
Mitochondrial function in normal and diabetic beta-cells.
Nature - 13 Dec 2001
Maechler P, Wollheim C B
Abstract excerpt
The aetiology of type 2, or non-insulin-dependent, diabetes mellitus has been characterized in only a limited number of cases. Among these, mitochondrial diabetes, a rare subform of the disease, is the consequence of pancreatic beta-cell dysfunction caused by mutations in mitochondrial DNA, which is distinct from the nuclear genome. The impact of such mutations on beta-cell function reflects the importance of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.