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Article

Mitochondrial diabetes mellitus.

Journal of endocrinological investigation - 1 May 2002

Maassen J A, Janssen G M C, Lemkes H H J P

Abstract excerpt

This review discusses the current insight by which mutations in mitochondrial DNA (mtDNA) contribute to the development of particular disease states with emphasis on diabetes mellitus. Mitochondria are the power factories of the cells and produce ATP by oxidizing reducing equivalents via the respiratory chain. These reducing equivalents originate mainly from the citric acid cycle that also occurs within the...

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Diabetes Mellitus
DNA, Mitochondrial
Gene Frequency
Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12035948
DOI: 10.1007/BF03344042

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