Article
Mitochondrial diabetes mellitus.
Journal of endocrinological investigation - 1 May 2002
Maassen J A, Janssen G M C, Lemkes H H J P
Abstract excerpt
This review discusses the current insight by which mutations in mitochondrial DNA (mtDNA) contribute to the development of particular disease states with emphasis on diabetes mellitus. Mitochondria are the power factories of the cells and produce ATP by oxidizing reducing equivalents via the respiratory chain. These reducing equivalents originate mainly from the citric acid cycle that also occurs within the...
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