Article
Essential contribution of germline-encoded lysine residues in Jgamma1.2 segment to the recognition of nonpeptide antigens by human gammadelta T cells.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2001
Miyagawa F, Tanaka Y, Yamashita S, Mikami B, Danno K, Uehara M, Minato N
Abstract excerpt
Human gammadelta T cells display unique repertoires of Ag specificities largely imposed by selective usages of distinct Vgamma and Vdelta genes. Among them, Vgamma2/Vdelta2(+) T cells predominate in the circulation of healthy adults and respond to various microbial small molecular mass nonpeptide Ags. The present results indicate that the primary Vgamma2/Vdelta2(+) T cells stimulated with the distinct groups of...
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