Article
Molecular karyotyping for detection of prognostic markers in fine needle aspiration biopsy samples of uveal melanoma.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Ganguly Arupa, Richards-Yutz Jennifer, Ewens Kathryn G
Abstract excerpt
Uveal melanoma is the most common cancer of the eye in which approximately 50 % of cases develop metastases that are fatal within 2-15 years. Thus it is critical to identify prognostic markers to select high-risk patients into an adjuvant treatment. Chromosomal copy number alterations have been associated with poor prognosis. Historically the gold standard for identifying chromosomal aberrations had been...
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