Article
Cryoglobulinemic glomerulonephritis in thymic stromal lymphopoietin transgenic mice.
The American journal of pathology - 1 Dec 2001
Taneda S, Segerer S, Hudkins K L, Cui Y, Wen M, Segerer M, Wener M H, Khairallah C G, Farr A G, Alpers C E
Abstract excerpt
Mixed cryoglobulins are complexes of immunoglobulins that reversibly precipitate in the cold and lead to a systemic disease in humans. Renal involvement usually manifests as a membranoproliferative glomerulonephritis with marked monocyte infiltration and, at times, intracapillary thrombi. Thymic stromal lymphopoietin (TSLP) is a recently cloned cytokine that supports differentiation and long-term growth of B...
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