Article
A biologic model to study the genetics of psychotic, mood, and anxiety disorders: the velocardiofacial syndrome.
Current psychiatry reports - 1 Apr 2006
Jolin Edith M, Weller Elizabeth B, Weller Ronald A
Abstract excerpt
Recent advances in molecular genetics have led to new insights on the velocardiofacial syndrome (VCFS). Most patients have a large deletion on one copy of chromosome 22 (encompassing up to 30 genes), which can be confirmed with genetic testing. A wide spectrum of psychiatric symptoms has been reported in patients with VCFS, including schizophrenia and bipolar disorder. Preliminary studies of candidate genes from...
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