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Article

Control of branch-site choice by a group II intron.

The EMBO journal - 3 Dec 2001

Chu V T, Adamidi C, Liu Q, Perlman P S, Pyle A M

Abstract excerpt

The branch site of group II introns is typically a bulged adenosine near the 3'-end of intron domain 6. The branch site is chosen with extraordinarily high fidelity, even when the adenosine is mutated to other bases or if the typically bulged adenosine is paired. Given these facts, it has been difficult to discern the mechanism by which the proper branch site is chosen. In order to dissect the determinants for...

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Identifiers

PMID: 11726522
DOI: 10.1093/emboj/20.23.6866
PMCID: PMC125754

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Source receipt: pubmed, retrieved 7 Sept 2026.

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