Article
Influence of heredity on human sensitivity to environmental chemicals.
Environmental and molecular mutagenesis - 1 Jan 1995
Weber W W
Abstract excerpt
Hereditary peculiarities in individual responses to environmental chemicals are a common occurrence in human populations. Genetic variation in glutathione S-transferase, CYP1A2, N-acetyltransferase, and paraoxonase exemplify the relationship of metabolic variation to individual susceptibility to cancer and other toxicants of environmental origin. Heritable receptor protein variants, a subset of proteins of...
Topics
- Carcinogens, Environmental
- Environmental Pollutants
- Enzymes
- Genetic Diseases, Inborn
- Genetic Variation
- Humans
- Pharmacogenetics
