Article
Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest.
The Journal of biological chemistry - 1 Mar 2002
Yoshii Tadashi, Fukumori Tomoharu, Honjo Yuichiro, Inohara Hidenori, Kim Hyeong-Reh Choi, Raz Avraham
Abstract excerpt
Galectin-3, a beta-galactoside-binding protein, is implicated in cell growth, adhesion, differentiation, and tumor progression by interactions with its ligands. Recent studies have revealed that galectin-3 suppresses apoptosis and anoikis that contribute to cell survival during metastatic cascades. Previously, it has been shown that human galectin-3 undergoes post-translational signaling modification of Ser(6)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
