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Article

Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons.

Applied and environmental microbiology - 1 Dec 2001

Li Q S, Ogawa J, Schmid R D, Shimizu S

Abstract excerpt

Cytochrome P450 BM-3, a self-sufficient P450 enzyme from Bacillus megaterium that catalyzes the subterminal hydroxylation of long-chain fatty acids, has been engineered into a catalyst for the oxidation of polycyclic aromatic hydrocarbons. The activities of a triplet mutant (A74G/F87V/L188Q) towards naphthalene, fluorene, acenaphthene, acenaphthylene, and 9-methylanthracene were 160, 53, 109, 287, and 22/min,...

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Source

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Identifiers

PMID: 11722930
DOI: 10.1128/AEM.67.12.5735-5739.2001
PMCID: PMC93367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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