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Article

Limited recombination events in merozoite surface protein-1 alleles of Plasmodium falciparum on islands.

Gene - 14 Nov 2001

Sakihama N, Kaneko A, Hattori T, Tanabe K

Abstract excerpt

Intragenic recombination is a principal mechanism for the generation of allelic variation in the merozoite surface protein-1 gene (Msp-1) of the human malaria parasite Plasmodium falciparum. In the present study, linkage disequilibrium between the 5'- and 3'-polymorphic sites was analyzed to determine the frequency of recombination events in Msp-1 in parasite populations on four islands in Vanuatu, the...

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Source

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PMID: 11722844
DOI: 10.1016/s0378-1119(01)00748-x

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