Article
Automated detection of the G20210A prothrombin mutation using the LCx microparticle enzyme immunoassay.
Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2001
Gilchrist A, Solomon N, Erickson D, Sikand A, Bauer K A, Kruskall M S, Kocher O
Abstract excerpt
BACKGROUND: The prothrombin mutation, a G/A transition at position 20210 in the 3' untranslated region of the prothrombin gene, is associated with an increased risk of deep venous thrombosis and obstetrical complications. Several methods have been developed to detect the mutation; however, given the increased demand for this test in risk factor assessment, the development of simple and efficient screening methods...
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