Article
The relationship between MTHFR gene polymorphisms, plasma homocysteine levels and diabetic retinopathy in type 2 diabetes mellitus.
Chinese medical journal - 1 Jan 2003
Sun Jiazhong, Xu Yancheng, Zhu Yilian, Lu Hongyun, Deng Haohua, Fan Youyun, Sun Suxin, Zhang Ying
Abstract excerpt
OBJECTIVE: To evaluate the role of methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and plasma homocysteine levels in patients with type 2 diabetes mellitus and diabetic retinopathy (DR). METHODS: Total of 208 patients with type 2 diabetes mellitus and 57 controls were recruited into the study. MTHFR genetic C677T polymorphisms were determined by PCR-RFLP. Plasma total homocysteine levels were...
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