Article
Lack of association between hepatocyte nuclear factor-1beta gene and common forms of type 2 diabetes in the Japanese population.
Diabetes, nutrition & metabolism - 1 Aug 2001
Babaya N, Ikegami H, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Itoi-Babaya M, Taniguchi H, Noso S, Horiki M, Yamada K, Kawaguchi Y, Fukuda M, Ogihara T
Abstract excerpt
Mutations in the hepatocyte nuclear factor-1beta (HNF-1beta) gene have been shown to be a cause of maturity-onset diabetes of the young (MODY). We studied the contribution of the HNF-1beta gene to susceptibility to common forms of Type 2 diabetes in the genetically homogeneous Japanese population, by investigating the allelic association of Type 2 diabetes with two markers in the HNF-1beta region. The frequency...
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