Article
Hepatocyte nuclear factor-1alpha gene and non-insulin-dependent diabetes mellitus in the Japanese population.
Acta diabetologica - 1 Oct 1998
Babaya N, Ikegami H, Kawaguchi Y, Fujisawa T, Nakagawa Y, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Yamada K, Shen G Q, Fukuda M, Ogihara T
Abstract excerpt
Recently, hepatocyte nuclear factor-1alpha(HNF-1alpha, which is encoded by the TCF1 gene) mutations were reported in a subset of patients with maturity onset diabetes of the young (MODY3). We studied the contribution of TCF1 to genetic susceptibility to common non-insulin-dependent diabetes melli...
Topics
- Adult
- Age of Onset
- DNA
- DNA-Binding Proteins
- Diabetes Mellitus, Type 2
- Gene Frequency
- Genetic Markers
- Genetic Predisposition to Disease
- Hepatocyte Nuclear Factor 1
- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1-beta
- Humans
- Japan