Article
Hepatocyte nuclear factor-1alpha gene and non-insulin-dependent diabetes mellitus in the Japanese population.
Acta diabetologica - 1 Oct 1998
Babaya N, Ikegami H, Kawaguchi Y, Fujisawa T, Nakagawa Y, Hamada Y, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Yamada K, Shen G Q, Fukuda M, Ogihara T
Abstract excerpt
Recently, hepatocyte nuclear factor-1alpha(HNF-1alpha, which is encoded by the TCF1 gene) mutations were reported in a subset of patients with maturity onset diabetes of the young (MODY3). We studied the contribution of TCF1 to genetic susceptibility to common non-insulin-dependent diabetes mellitus (type 2) in Japanese subjects by investigating allelic association with type 2 diabetes use of three markers. We...
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