Article
No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
Diabetologia - 1 Aug 2000
Hara M, Wang X, Paz V P, Cox N J, Iwasaki N, Ogata M, Iwamoto Y, Bell G I
Abstract excerpt
AIMS/HYPOTHESIS: Mutations in the transcription factor hepatocyte nuclear factor (HNF)-4alpha are the cause of one form of maturity-onset diabetes of the young, MODY1. The HNF-4gamma is structurally related to HNF-4alpha and is expressed together with HNF-4alpha in pancreatic islets. We therefore tested the hypothesis that genetic variation in the HNF-4gamma gene (HNF4G) is associated with MODY in Japanese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
