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Article

Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection

1 Dec 2001

Abstract excerpt

The effects of HIV infection upon the thymus and peripheral T cell turnover have been implicated in the pathogenesis of AIDS. In this study, we investigated whether decreased thymic output, increased T cell proliferation, or both can occur in HIV infection. We measured peripheral blood levels of TCR rearrangement excision circles (TREC) and parameters of cell proliferation, including Ki67 expression and ex vivo...

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Identifiers

PMID: 11714838
DOI: 10.4049/jimmunol.167.11.6663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV InfectionPMID 11714838Read ↗

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