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Article

Analysis of telomere length and thymic output in fast and slow/non-progressors with HIV infection.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2000

Richardson M W, Sverstiuk A, Hendel H, Cheung T W, Zagury J F, Rappaport J

Abstract excerpt

There are two models for CD4+ T-cell depletion leading to AIDS: a kinetic model and an immune suppression model. In the kinetic model, direct cell killing due to viral replication results in a continuous demand for CD4+ T-cells, which eventually exhausts their capacity for renewal by proliferative mechanisms. In the immune suppression model, CD4+ T-cell decline is due to an indirect global inhibitory effect of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10721459
DOI: 10.1016/s0753-3322(00)88637-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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