Article
Multiple lysosomal trafficking phenotypes in metastatic mouse mammary tumor cell lines.
International journal of oncology - 1 Dec 2001
Tao K, Li J, Warner J, MacLeod K, Miller F R, Sahagian G G
Abstract excerpt
Although altered synthesis and trafficking of lysosomal proteins and their receptors are associated with a wide range of human and rodent malignancies, the basis for their involvement remains obscure. Here we describe findings on a set of mouse mammary tumor cell lines that we are using as a model to study the role of these proteins in oncogenesis and tumor progression. Three distinct proteinase-secreting...
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