Article
Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila.
Genes & development - 15 Nov 2001
Razzaq A, Robinson I M, McMahon H T, Skepper J N, Su Y, Zelhof A C, Jackson A P, Gay N J, O'Kane C J
Abstract excerpt
Amphiphysins 1 and 2 are enriched in the mammalian brain and are proposed to recruit dynamin to sites of endocytosis. Shorter amphiphysin 2 splice variants are also found ubiquitously, with an enrichment in skeletal muscle. At the Drosophila larval neuromuscular junction, amphiphysin is localized postsynaptically and amphiphysin mutants have no major defects in neurotransmission; they are also viable, but...
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