Article
A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicron.
Antimicrobial agents and chemotherapy - 1 Dec 2001
Miyamae S, Ueda O, Yoshimura F, Hwang J, Tanaka Y, Nikaido H
Abstract excerpt
We cloned a gene, bexA, that codes for a multidrug efflux transporter from the chromosomal DNA of Bacteroides thetaiotaomicron ATCC 29741 by using an Escherichia coli DeltaacrAB DeltaacrEF mutant as a host. Although the initial recombinant construct contained other open reading frames, the presen...
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