Article
Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila.
Developmental cell - 1 Nov 2001
Chen E H, Olson E N
Abstract excerpt
Somatic muscle formation in Drosophila requires fusion of muscle founder cells with fusion-competent myoblasts. In a genetic screen for genes that control muscle development, we identified antisocial (ants), a gene that encodes an ankyrin repeat-, TPR repeat-, and RING finger-containing protein, required for myoblast fusion. In ants mutant embryos, founder cells and fusion-competent myoblasts are properly...
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