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Article

Do muscle founder cells exist in vertebrates?

Trends in cell biology - 1 Aug 2012

Powell Gareth T, Wright Gavin J

Abstract excerpt

Skeletal muscle is formed by the iterative fusion of precursor cells (myocytes) into long multinuclear fibres. Extensive studies of fusion in Drosophila embryos have lead to a paradigm in which myoblasts are divided into two distinct subtypes - founder and fusion-competent myoblasts (FCMs) - that can fuse to each other, but not among themselves. Only founder cells can direct the formation of muscle fibres, while...

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Identifiers

PMID: 22710008
DOI: 10.1016/j.tcb.2012.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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