Article
An association between the Trp64Arg polymorphism in the beta3-adrenergic receptor gene and endometrial cancer and obesity.
Journal of experimental & clinical cancer research : CR - 1 Dec 2004
Babol K, Przybylowska K, Lukaszek M, Pertynski T, Blasiak J
Abstract excerpt
Beta3-adrenergic receptor (beta3AR) stimulates lipolysis in human fat cells, so its gene can constitute a candidate to explain a part of genetic predisposition to human obesity and related disorders. The Trp64Arg polymorphism in the beta3AR gene has been reported to be associated with insulin resistance, obesity and type 2 diabetes; little is known about its possible association with cancer. To check this...
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