Article
Plasmodium falciparum genotypes, low complexity of infection, and resistance to subsequent malaria in participants in the Asembo Bay Cohort Project.
Infection and immunity - 1 Dec 2001
Branch O H, Takala S, Kariuki S, Nahlen B L, Kolczak M, Hawley W, Lal A A
Abstract excerpt
To assess the relationship between the within-host diversity of malaria infections and the susceptibility of the host to subsequent infection, we genotyped 60 children's successive infections from birth through 3 years of life. MSP-1 Block2 genotypes were used to estimate the complexity of infection (COI). Malaria transmission and age were positively associated with the number of K1 and Mad20 alleles detected...
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