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Article

Role of glucan and surface protein BAD1 in complement activation by Blastomyces dermatitidis yeast.

Infection and immunity - 1 Dec 2001

Zhang M X, Brandhorst T T, Kozel T R, Klein B S

Abstract excerpt

Our previous studies showed that Blastomyces dermatitidis yeast activates the human complement system, leading to deposition of opsonic complement fragments onto the yeast surface. This report examines the influence of altered surface expression of glucan or BAD1 protein (formerly WI-1) on the yeast's ability to activate and bind C3. Compared to the wild type, a glucan-deficient mutant yeast delayed initiation of...

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Identifiers

PMID: 11705933
DOI: 10.1128/IAI.69.12.7559-7564.2001
PMCID: PMC98847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of glucan and surface protein BAD1 in complement activation by Blastomyces dermatitidis yeast.PMID 11705933Read ↗

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