Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms.

American journal of human genetics - 1 Dec 2001

Uhl G R, Liu Q R, Walther D, Hess J, Naiman D

Abstract excerpt

Strong genetic contributions to drug abuse vulnerability are well documented, but few chromosomal locations for human drug-abuse vulnerability alleles have been confirmed. We now identify chromosomal markers whose alleles distinguish drug abusers from control individuals in each of two samples, on the basis of pooled-sample microarray and association analyses. Reproducibly positive chromosomal regions defined by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa
Share to Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alcohol-Related Disorders

Share to Brain-Derived Neurotrophic Factor

Share to Chromosomes, Human

Share to Nicotine

Share to Radiation Hybrid Mapping

Share to Substance-Related Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 11704927
DOI: 10.1086/324467
PMCID: PMC1235541

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms.PMID 11704927Read ↗

Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples.Semantic proximity Read ↗

Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results.Semantic proximity Read ↗

Molecular genetic underpinnings of human substance abuse vulnerability: likely contributions to understanding addiction as a mnemonic process.Semantic proximity Read ↗

Genetics of Substance Use Disorders.Semantic proximity Read ↗

Strategies for identifying genes underlying drug abuse susceptibility.Semantic proximity Read ↗

Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects.Semantic proximity Read ↗

Recent Efforts to Dissect the Genetic Basis of Alcohol Use and Abuse.Semantic proximity Read ↗

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women.Semantic proximity Read ↗

Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence.Semantic proximity Read ↗

Phenome-wide Association Analysis of Substance Use Disorders in a Deeply Phenotyped Sample.Semantic proximity Read ↗

Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples.Semantic proximity Read ↗

Rare nonsynonymous exonic variants in addiction and behavioral disinhibition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.