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Article

Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence.

Journal of neurogenetics - 1 Jan 2009

Uhl George R, Drgon Tomas, Johnson Catherine, Liu Qing-Rong

Abstract excerpt

Abundant evidence from family, adoption, and twin studies point to large genetic contributions to individual differences in vulnerability to develop dependence on one or more addictive substances. Twin data suggest that most of this genetic vulnerability is shared by individuals who are dependent on a variety of addictive substances. Molecular genetic studies, especially genomewide and candidate gene association...

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Identifiers

PMID: 19152208
DOI: 10.1080/01677060802572929
PMCID: PMC4898946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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