Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs.

Abstract excerpt

Individual differences in drug effects and treatment response are relatively enduring, continuously distributed, as well as substantially heritable, and are therefore likely to result from an interplay of multiple genomic variations with environmental influences. As the etiology and pathogenesis of behavioral and psychiatric disorders is genetically complex, so is the response to drug treatment....

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