Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology.

Journal of psychiatry & neuroscience : JPN - 1 Jan 2015

Booij Linda, Tremblay Richard E, Szyf Moshe, Benkelfat Chawki

Abstract excerpt

BACKGROUND: Despite more than 60 years of research in the role of serotonin (5-HT) in psychopathology, many questions still remain. From a developmental perspective, studies have provided more insight into how 5-HT dysfunctions acquired in utero or early in life may modulate brain development. This paper discusses the relevance of the developmental role of 5-HT for the understanding of psychopathology. We review...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Environment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene-Environment Interaction

Share to Genetic Predisposition to Disease

Share to Mental Disorders

Share to Serotonin

Source

Open in PubMed Open full text

Identifiers

PMID: 25285876
DOI: 10.1503/jpn.140099
PMCID: PMC4275332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology.PMID 25285876Read ↗

Serotonin-related pathways and developmental plasticity: relevance for psychiatric disorders.Semantic proximity Read ↗

New Insights into How Serotonin Selective Reuptake Inhibitors Shape the Developing BrainSemantic proximity Read ↗

Gestational Factors throughout Fetal Neurodevelopment: The Serotonin LinkSemantic proximity Read ↗

Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?Semantic proximity Read ↗

Serotonin, genetic variability, behaviour, and psychiatric disorders--a review.Semantic proximity Read ↗

New lessons from knockout mice: The role of serotonin during development and its possible contribution to the origins of neuropsychiatric disorders.Semantic proximity Read ↗

Experience-based brain development: Scientific underpinnings of the importance of early child development in a global worldSemantic proximity Read ↗

Pharmacogenetics of the serotonin transporter.Semantic proximity Read ↗

Perinatal serotonin signalling dynamically influences the development of cortical GABAergic circuits with consequences for lifelong sensory encodingSemantic proximity Read ↗

Neuronal and behavioral plasticity: the role of serotonin and BDNF systems tandemSemantic proximity Read ↗

The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric OutcomesSemantic proximity Read ↗

Early environmental influences on the development of children's brain structure and functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.