Article
Antisense RNA regulation of the par post-segregational killing system: structural analysis and mechanism of binding of the antisense RNA, RNAII and its target, RNAI.
Molecular microbiology - 1 Oct 2001
Greenfield T J, Franch T, Gerdes K, Weaver K E
Abstract excerpt
The par stability determinant of the Enterococcus faecalis plasmid pAD1 is the first antisense RNA regulated post-segregational killing system (PSK) identified in a Gram-positive organism. Par encodes two small, convergently transcribed RNAs, designated RNAI and RNAII, which are the toxin and antitoxin of the par PSK system respectively. RNAI encodes an open reading frame for a 33 amino acid toxin called Fst....
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Binding, Competitive
- Enterococcus faecalis
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Nuclease Protection Assays
- Nucleic Acid Conformation
- Nucleic Acid Hybridization
- Open Reading Frames