Article
Activation of alpha-toxin translation in Staphylococcus aureus by the trans-encoded antisense RNA, RNAIII.
The EMBO journal - 15 Sept 1995
Morfeldt E, Taylor D, von Gabain A, Arvidson S
Abstract excerpt
The synthesis of virulence factors in Staphylococcus aureus is controlled by a regulatory RNA molecule, RNAIII, encoded by the agr locus. Transcription of genes coding for secreted toxins and enzymes is stimulated, while transcription of cell-surface protein genes is repressed by RNAIII. In the c...
Topics
- Bacterial Toxins
- Base Sequence
- Blotting, Northern
- Electrophoresis, Agar Gel
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation, Bacterial
- Hemolysin Proteins
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Biosynthesis
- RNA, Antisense
- RNA, Bacterial
- RNA, Messenger
- Sequence Analysis, DNA
- Staphylococcus aureus