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Article

Enterococcus faecalis plasmid pAD1-encoded Fst toxin affects membrane permeability and alters cellular responses to lantibiotics.

Journal of bacteriology - 1 Apr 2003

Weaver Keith E, Weaver Dariel M, Wells Carol L, Waters Christopher M, Gardner Marshall E, Ehli Erik A

Abstract excerpt

Fst is a peptide toxin encoded by the par toxin-antitoxin stability determinant of Enterococcus faecalis plasmid pAD1. Intracellular overproduction of Fst resulted in simultaneous inhibition of all cellular macromolecular synthesis concomitant with cell growth inhibition and compromised the integrity of the cell membrane. Cells did not lyse or noticeably leak intracellular contents but had specific defects in...

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Identifiers

PMID: 12644486
DOI: 10.1128/JB.185.7.2169-2177.2003
PMCID: PMC151501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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