Article
Muscular degeneration in the absence of dystrophin is a calcium-dependent process.
Current biology : CB - 30 Oct 2001
Mariol M C, Ségalat L
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a progressive degenerative muscular disease that is due to mutations in the dystrophin gene. Neither the function of dystrophin nor the physiopathology of the disease have been clearly established yet. Several groups have reported elevated calcium concentrations in the mdx mouse model of DMD, but the effect of calcium levels on the progression of the disease continues to be a...
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