Article
Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans.
Current biology : CB - 21 Sept 2000
Gieseler K, Grisoni K, Ségalat L
Abstract excerpt
BACKGROUND: Dystrophin is the product of the gene that is mutated in Duchenne muscular dystrophy (DMD), a progressive neuromuscular disease for which no treatment is available. Mice carrying a mutation in the gene for dystrophin (mdx mice) display only a mild phenotype, but it is aggravated when...
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