Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Apr 2014

Nagarajan Archana, Ning Ye, Reisner Kaja, Buraei Zafir, Larsen Jan Petter, Hobert Oliver, Doitsidou Maria

Abstract excerpt

Progressive neurodegenerative diseases are among the most frequently occurring aging-associated human pathologies. In a screen for Caenorhabditis elegans mutant animals that lack their normal complement of dopaminergic neurons, we identified two strains with progressive loss of dopaminergic neuro...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopaminergic Neurons

Share to Movement

Share to Mutation

Share to Nerve Degeneration

Share to TRPC Cation Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 24760834
DOI: 10.1523/JNEUROSCI.4540-13.2014
PMCID: PMC3996206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24760834-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death.PMID 24760834Read ↗

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's diseaseSemantic proximity Read ↗

Modeling Parkinson's Disease in C. elegans.Semantic proximity Read ↗

Exploring Caenorhabditis elegans as Parkinson’s Disease Model: Neurotoxins and Genetic ImplicationsSemantic proximity Read ↗

Systematic Review of Caenorhabditis elegans Models for Mechanism Research and Drug Discovery in Parkinson’s DiseaseSemantic proximity Read ↗

Caenorhabditis elegans as a Model System to Study Human Neurodegenerative DisordersSemantic proximity Read ↗

Neuronal aging: learning from C. elegansSemantic proximity Read ↗

Modelling Parkinson's Disease in C. elegans : Strengths and LimitationsSemantic proximity Read ↗

Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson’s disease, Alzheimer’s disease and autism spectrum disorderSemantic proximity Read ↗

Functional Screening of Parkinson’s Disease Susceptibility Genes to Identify Novel Modulators of α-Synuclein Neurotoxicity in Caenorhabditis elegansSemantic proximity Read ↗

Staphylococcus aureus-Induced Degeneration of Nociceptive Neurons in Caenorhabditis elegansSemantic proximity Read ↗

Sink or swim: Does a worm paralysis phenotype hold clues to neurodegenerative disease?Semantic proximity Read ↗

Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.