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Article

Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Apr 2014

Nagarajan Archana, Ning Ye, Reisner Kaja, Buraei Zafir, Larsen Jan Petter, Hobert Oliver, Doitsidou Maria

Abstract excerpt

Progressive neurodegenerative diseases are among the most frequently occurring aging-associated human pathologies. In a screen for Caenorhabditis elegans mutant animals that lack their normal complement of dopaminergic neurons, we identified two strains with progressive loss of dopaminergic neurons during postembryonic life. Through whole-genome sequencing we show that both strains harbor dominant (d),...

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Identifiers

PMID: 24760834
DOI: 10.1523/JNEUROSCI.4540-13.2014
PMCID: PMC3996206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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