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Article

Differential Developmental Ability of Embryos Cloned from Tissue-Specific Stem Cells

25 Jan 2007

Abstract excerpt

Although cloning animals by somatic cell nuclear transfer is generally inefficient, the use of certain nuclear donor cell types may significantly improve or deteriorate outcomes. We evaluated whether two multipotent stem cell lines produced in vitro--neural stem cells (NSCs) and mesenchymal stem cells (MSCs)--could serve as nuclear donors for nuclear transfer cloning. Most (76%) NSC-derived embryos survived the...

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PMID: 17255518
DOI: 10.1634/stemcells.2006-0747

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