Angiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population.

doi:10.1161/01.atv.19.8.1969

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Article

Angiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1999

Hung J, McQuillan B M, Nidorf M, Thompson P L, Beilby J P

Abstract excerpt

The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene has been associated with an increased risk of coronary heart disease, but whether it is a risk factor for underlying atherosclerosis remains unclear. Therefore, we examined to see whether the ACE gene deletion polymorphism was associated with carotid wall thickening and atherosclerotic plaque formation in a large randomly...

Topics

Adult
Aged
Alleles
Carotid Arteries
Female
Gene Frequency
Genotype
Humans
Logistic Models
Male
Middle Aged
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Tunica Intima
Tunica Media
Ultrasonography

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PMID: 10446079
DOI: 10.1161/01.atv.19.8.1969

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