Article
Interdomain but not intermolecular interactions observed in CFTR channels.
Biochemical and biophysical research communications - 9 Nov 2001
Kembi F, Harrington M A
Abstract excerpt
Gating of the cystic fibrosis transmembrane conductance regulator (CFTR) channels requires interdomain and/or intermolecular interactions involving different parts of the protein, yet the exact nature of those interactions remains unclear. In this study we report that treating wild type CFTR-expressing cells with oxidizing agents results in a significant reduction in the gel mobility of the protein indicative of...
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