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Article

Real-time quantitative PCR analysis for alpha-thalassemia-1 of Southeast Asian type deletion in Taiwan.

Clinical genetics - 1 Oct 2001

Sun C F, Lee C H, Cheng S W, Lin M H, Wu T L, Tsao K C, Chiu D T, Liou J D, Chu D C

Abstract excerpt

Since homozygosity of the alpha-thalassemia-1 of Southeast Asian (SEA) type deletion results in hydrops fetalis, a novel protocol based on the real-time quantitating polymerase chain reaction (PCR) technique has been developed to quantify the intact and aberrant alpha-globin genes in adults. The ratio of the normal/SEA-bearing alpha-globin genes was expressed in cycle threshold (C(T)) values. Theoretically, a...

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Source

Identifiers

PMID: 11683777
DOI: 10.1034/j.1399-0004.2001.600409.x

Genes

SEA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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